Life after pancreas removal surgery , also known as a pancreatectomy , brings significant changes to how your body functions. The pancreas plays a vital role in controlling blood sugar and producing enzymes that help digest food. Without it, patients must adapt to new routines, medications, and dietary habits to stay healthy. While surgery is sometimes necessary due to conditions like severe pancreatitis or cancer, it comes with lifelong adjustments. From managing diabetes with insulin to taking enzyme replacements and following a strict diet, recovery requires discipline and regular monitoring. Understanding these changes can make post-surgery life more manageable.
Lifestyle changes after pancreas removal
Once the pancreas is removed, your body can no longer naturally produce insulin or digestive enzymes . According to a study published in the Journal Nutrients, removing the pancreas affects the body in two big ways: it can no longer make insulin to control blood sugar and it can’t produce enzymes needed for digestion. This often leads to weight loss and poor nutrition after surgery. The research highlights that keeping blood sugar under control and following a proper nutrition plan are very important for avoiding early health problems after the operation.This means lifestyle modifications become crucial to maintain good health and prevent complications. Experts advise patients to adopt the following habits:
  • Avoid alcohol completely as it can worsen digestive issues and interfere with recovery.
  • Limit foods high in simple sugars since the absence of insulin makes blood sugar harder to control.
  • Cut back on greasy and fatty foods because your digestive system may struggle to process them without pancreatic enzymes.
  • Choose nutrient-dense drinks such as smoothies or shakes fortified with vitamins and protein.
  • Eat plenty of fruits and vegetables—about two to three cups daily for fibre and antioxidants.
  • Include healthy fats like olive oil, nuts, seeds, and avocado in moderation.

Hydration is equally important. Experts recommend drinking 6–12 cups of water or fluids daily. Meals should be smaller and more frequent, ideally six to eight times a day, spaced two to three hours apart. To avoid bloating or discomfort, doctors suggest sipping small amounts of fluid during meals and saving larger intakes for before or after eating.
In addition, most people who undergo pancreas removal develop diabetes and require insulin replacement therapy . Enzyme replacement medications may also be prescribed to help the digestive system absorb nutrients effectively. These adjustments are critical for preventing malnutrition and maintaining stable blood sugar levels.
Possible complications after pancreas removal
Although surgery may resolve the underlying condition that led to pancreas removal, it can also cause new health challenges. Many patients need hospitalisation shortly after the procedure to stabilise blood sugar or manage digestive issues. Some of the most common complications include:
  • Digestive tract blockages leading to bowel obstruction.
  • Hernias, which may develop after major abdominal surgery.
  • Bile duct problems, sometimes requiring endoscopic procedures such as ERCP (endoscopic retrograde cholangiopancreatography).

These complications highlight the importance of working closely with your healthcare team. Regular follow-ups allow doctors to adjust medications, recommend suitable diets, and detect problems early before they become more severe.
How pancreas removal affects life expectancy
The impact of a pancreatectomy on life expectancy depends on several factors, including age, overall health, the type of surgery performed, and the medical condition that required removal of the pancreas.
For example, patients who undergo surgery due to chronic pancreatitis generally have favourable outcomes, with survival rates of over 80% at five years and around 63% at ten years after surgery. However, they remain at risk of complications such as infections, cardiovascular disease, and long-term diabetes.
In contrast, patients who undergo pancreas removal for pancreatic cancer often face more serious challenges. Statistics show that more than 6% of patients may not survive beyond 90 days after surgery, and up to 20% may pass away within a year. This is largely due to the aggressive nature of pancreatic cancer and related complications. Overall, while living without a pancreas is difficult, outcomes vary widely depending on the underlying condition, post-surgery care, and adherence to medical advice.
Long-term care after pancreas removal: Why regular check-ups are essential
After pancreas removal, recovery is not limited to the immediate weeks after surgery—it requires lifelong monitoring. Health care professionals usually provide strict instructions on diet, medication, and physical activity during the recovery period. Following these guidelines is essential for long-term health.
Short-term side effects such as diarrhoea, bloating, and gas are common in the first year but often improve with time and enzyme replacement therapy. Long-term care focuses on three main areas:
  • Hormone monitoring to check insulin and glucose regulation.
  • Digestive health to ensure nutrients are absorbed properly.
  • Regular blood tests and scans to identify any complications early.

By staying consistent with follow-up appointments and medical checks, patients can significantly improve their quality of life and reduce risks associated with living without a pancreas.
Disclaimer: This article is for general informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider regarding any medical condition or lifestyle change.
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